Hotel Santa Irene is set in Cholula, 14 km from Puebla Convention Centre and 16 km from Cuauhtemoc Stadium. The property is around 11 km from Estrella de Puebla, 12 km from International Museum of the Baroque and 13 km from Biblioteca Palafoxiana. The property is non-smoking and is situated 16 km from Acropolis Puebla.
All rooms in the hotel are equipped with a flat-screen TV with satellite channels. With a private bathroom fitted with a shower and free toiletries, rooms at Hotel Santa Irene also feature free WiFi. At the accommodation the rooms have bed linen and towels.
Hotel Santa Irene offers a sun terrace.
Puebla Metropolitan Arena is 11 km from the hotel, while BUAP Cultural Complex is 12 km from the property. The nearest airport is Hermanos Serdán International Airport, 11 km from Hotel Santa Irene.